acute graft-versus host disease
Histologic Features
- Epidermal thinning
- Many individual necrotic keratinocytes surrounded by lymphocytes
- Vacuolar alterations of the basal layer
- Scattered melanophages in the papillary dermis
- A sparse superficial perivascular infiltrate of lymphocytes
- Subepiderma1 vesiculation
- Sclerosis of the papillary dermis and loss of adnexal structures (late)
- Dyskeratosis involving the follicular epithelium
Updated Wednesday, July 31, 2013 8:30:48 PM